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Epigenetic modification slows aging in yeast

Published on 3rd Aug 2015

Published on 3rd August 2015

Aging in Saccharomyces cerevisiae can be modulated by regulating epigenetic histones that control gene expression.

Scientists at the Perelman School of Medicine at the University of Pennsylvania showed that abnormal transcription in aging cells that is mediated by chemical modifications on histones leads to shortened lifespan. Furthermore, reduction of this type of abnormal transcription leads to longevity in yeast.

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