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Top US Researchers Plan to Test a Pill to Prevent or Delay Alzheimer’s, Heart Disease and other Ailments that Come with Age

by Ricky Piper Published on 17th Mar 2015

by Ricky Piper Published on 17th March 2015

The trial which aims to test the drug metformin, a common medication often used to treat Type 2 diabetes, and see if it can delay or prevent other chronic diseases will be conducted at multiple research centers over five years, and will involve a randomised, controlled clinical trial using 1,000 elderly participants. 

“Aging is the major risk factor for all these diseases—heart disease, cancer, diabetes and Alzheimer’s,” said Nir Barzilai, director of the Institute for Aging Research at Albert Einstein College of Medicine in New York City who is leading the proposed study. “If you want to make a real impact you have to modulate the risk of aging and by that the risk for all those diseases of aging.”

The scientists say that if TAME is a well-designed, large-scale study, the US Food and Drug Administration might be persuaded to consider aging as an indication, or preventable condition, a move that could spur drug makers to target factors that contribute to aging.

Continue reading @ Wall Street Journal